Statin Intolerance

Statin Intolerance.pptx (sharepoint.com)

Diagnosis and Management of Statin Intolerance - PubMed (nih.gov)

Efficacy and Tolerability of non-daily Statin Administration: A Systematic Review of Literature | Journal of Contemporary Pharmacy Practice (allenpress.com)

Efficacy and tolerability of once-weekly rosuvastatin in patients with previous statin intolerance

Statins in Older Patients

Clinical Controversy Statins Geriatrics_final.pptx (sharepoint.com)

Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years: A Meta-analysis - PubMed (nih.gov)

  • In older adults without CVD, treating 100 (NNT) persons with statins for 2.5 years time-to-benefit prevented 1 MACE 

Risk Calculators

Statin Choice Decision AID - Site (mayoclinic.org)

Calibration and discrimination of the Framingham Risk Score and the Pooled Cohort Equations - PubMed (nih.gov)

  • The predicted event rate of 5.78% by the Framingham Risk Score and 3.51% by the Pooled Cohort Equations at 5 years overestimated observed event rates by 101% and 115%, respectively

Health Disparities

Health Disparities Across the Continuum of ASCVD Risk - PMC (nih.gov)

Using Race with Caution in the ASCVD Calculator | AAFP

Podcasts

#10 Cholesterol, lipids, statins, fish oil. Become a Master Lipidologist. - The Curbsiders

#191 Lipids Update and Cardiovascular Risk Reduction with Erin Michos MD - The Curbsiders

Articles

Dyslipidemia Management for Cardiovascular Disease Prevention: Guidelines from the VA/DoD | AAFP

Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease: A Randomized Clinical Trial - PubMed (nih.gov)

Guidelines

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (ahajournals.org)

References

Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines [published correction appears in J Am Coll Cardiol. 2019 Jun 25;73(24):3237-3241]. J Am Coll Cardiol. 2019;73(24):e285-e350. doi:10.1016/j.jacc.2018.11.003