Lectures

Chronic Heart Failure Management - teachIM 

Podcasts

#230 Kittleson Rules Acute Heart Failure - The Curbsiders 

#292 Acute Heart Failure, CHF Triple Distilled - The Curbsiders 

2022 AHA/ACC/HFSA Heart Failur - Last Week in Medicine - Apple Podcasts 

Articles

Diagnosis and Evaluation of Heart Failure | AAFP 

Management of Heart Failure: Updated Guidelines From the AHA/ACC | AAFP 

Assessing the Race-Based of BiDil (hydralazine/isosorbide dinitrate): brody.indd 

Guidelines

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation 

Lanmark Trials

High vs low dose furosemide  

• DOSE Trial: Diuretic strategies in patients with acute decompensated heart failure - PubMed 

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload | New England Journal of Medicine 

Evidence for metoprolol succinate in HFrEF  

• MERIT-HF Trial: Effects of Controlled-Release Metoprolol on Total Mortality, Hospitalizations, and Well-being in Patients With Heart Failure: The Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF) | Cardiology | JAMA | JAMA Network  

Evidence for carvedilol in HFrEF  

• COPERNICUS Trial: Effect of Carvedilol on Survival in Severe Chronic Heart Failure | New England Journal of Medicine  

Evidence for bisoprolol in HFrEF  

• CIBIS-II Trial: The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial - The Lancet  

Evidence for sacubitril/valsartan in HFrEF  

• PARADIGM-HF Trial: Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure | New England Journal of Medicine 

Evidence for spironolactone in HFrEF  

• RALES Trial: The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure | New England Journal of Medicine 

Evidence for reduced hospitalizations for spironolactone in HFpEF  

• TOPCAT Trial: Spironolactone for Heart Failure with Preserved Ejection Fraction | New England Journal of Medicine 

Evidence for empagliflozin in HFrEF  

• EMPEROR-Reduced Trial: Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure | New England Journal of Medicine  

Evidence for empagliflozin in HFpEF 

• EMPEROR-Preserved Trial: Empagliflozin in Heart Failure with a Preserved Ejection Fraction | New England Journal of Medicine 

Evidence for dapagliflozin in HFrEF  

• DAPA-HF: Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction | New England Journal of Medicine 

Evidence for dapagliflozin in HFpEF 

• DELIVER Trial: Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction | New England Journal of Medicine 

Special thanks to Hannah Holloway, PharmD for the charts used